The polyurethane open-end belt is made of thermoplastic polyurethane material, which has high wear resistance. All kinds of reinforced cores ensure that it still keeps good motion ability in rotation, small production tolerance, reliable transmission of polyurethane open-end synchronous belt, and size stability. During the production process, a nylon layer is added to the tooth surface/back to ensure the operation specificity of the special application remains unchanged, and a polyurethane layer can be thickened on the back of the belt to prevent corrosion or high load.